Mark D Pegram Selected Research

A-Z-CINN 310

1/2003

Targeted prodrug treatment of HER-2-positive breast tumor cells using trastuzumab and paclitaxel linked by A-Z-CINN Linker.

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Mark D Pegram Research Topics

Disease

40	Breast Neoplasms (Breast Cancer) 01/2022 - 06/2002
35	Neoplasms (Cancer) 01/2021 - 06/2002
6	Disease Progression 04/2021 - 05/2004
3	Triple Negative Breast Neoplasms 01/2021 - 01/2017
2	Fatigue 01/2021 - 07/2008
2	Stomach Neoplasms (Stomach Cancer) 01/2021 - 01/2020
2	Genetic Predisposition to Disease (Genetic Predisposition) 01/2015 - 01/2015
2	Diarrhea 07/2008 - 09/2006
2	Lung Neoplasms (Lung Cancer) 12/2006 - 11/2005
2	Cardiotoxicity 10/2005 - 12/2004
1	B-Cell Lymphoma (Lymphoma, B Cell) 01/2021
1	Vomiting 01/2021
1	Nausea 01/2021
1	Neoplasm Micrometastasis 01/2020
1	Neoplasm Metastasis (Metastasis) 01/2019
1	Brain Neoplasms (Brain Tumor) 12/2016
1	Circulating Neoplastic Cells 03/2016
1	Leukemia 11/2014
1	Pathologic Complete Response 04/2013
1	Exanthema (Rash) 07/2008
1	Ovarian Neoplasms (Ovarian Cancer) 09/2006
1	Inflammatory Breast Neoplasms 04/2006

Drug/Important Bio-Agent (IBA)

17	Trastuzumab (Herceptin)FDA Link 01/2022 - 06/2002
9	Proteins (Proteins, Gene)FDA Link 01/2022 - 06/2002
9	Pharmaceutical PreparationsIBA 01/2021 - 05/2004
6	Paclitaxel (Taxol)FDA LinkGeneric 01/2019 - 01/2003
5	Docetaxel (Taxotere)FDA Link 01/2017 - 05/2004
4	EnzymesIBA 01/2020 - 09/2006
4	Biological ProductsIBA 01/2015 - 02/2006
4	Carboplatin (JM8)FDA LinkGeneric 01/2011 - 05/2004
3	Estrogen ReceptorsIBA 01/2022 - 05/2018
3	Monoclonal AntibodiesIBA 01/2021 - 06/2002
3	Ado-Trastuzumab EmtansineIBA 01/2021 - 01/2016
3	Biomarkers (Surrogate Marker)IBA 01/2021 - 03/2016
3	Hormones (Hormone)IBA 01/2021 - 12/2012
3	ProdrugsIBA 01/2020 - 01/2003
3	Messenger RNA (mRNA)IBA 01/2020 - 01/2016
3	PlatinumIBA 04/2013 - 05/2004
3	Lapatinib (GW572016)FDA Link 12/2012 - 02/2006
3	AnthracyclinesIBA 01/2009 - 12/2004
3	Cyclophosphamide (Cytoxan)FDA LinkGeneric 12/2007 - 08/2004
3	human ERBB2 proteinIBA 01/2007 - 04/2006
3	Cisplatin (Platino)FDA LinkGeneric 04/2006 - 05/2004
2	neratinibIBA 01/2022 - 12/2016
2	Protein Isoforms (Isoforms)IBA 01/2021 - 01/2018
2	Immunoconjugates (Immunoconjugate)IBA 01/2021 - 01/2020
2	pertuzumabIBA 01/2021 - 09/2006
2	Epidermal Growth Factor (EGF)IBA 01/2021 - 12/2012
2	magrolimabIBA 01/2021 - 01/2019
2	Phosphotransferases (Kinase)IBA 12/2012 - 02/2006
2	taxaneIBA 01/2009 - 08/2004
2	SaltsIBA 12/2004 - 05/2004
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 03/2004 - 06/2002
1	Fulvestrant (Faslodex)FDA Link 01/2022
1	margetuximabIBA 04/2021
1	RNA (Ribonucleic Acid)IBA 01/2021
1	CopperIBA 01/2021
1	Chelating AgentsIBA 01/2021
1	AntibodiesIBA 01/2021
1	MEDI4276IBA 01/2021
1	Estrogen Receptor alphaIBA 01/2021
1	Membrane Proteins (Integral Membrane Proteins)IBA 01/2021
1	Rituximab (Mabthera)FDA Link 01/2021
1	Aspartate Aminotransferases (Aspartate Transaminase)IBA 01/2021
1	tretazicarIBA 01/2020
1	multidrug resistance-associated protein 1IBA 01/2020
1	Single-Chain AntibodiesIBA 01/2020
1	VaccinesIBA 11/2019
1	Neoplasm Antigens (Tumor Antigens)IBA 11/2019
1	PF-05280014IBA 01/2019
1	Cadherins (E-Cadherin)IBA 01/2019
1	Biosimilar PharmaceuticalsIBA 01/2019
1	Poly(ADP-ribose) Polymerase InhibitorsIBA 05/2018
1	Oncogene Proteins (Oncogene Protein)IBA 01/2018
1	Amyloid Precursor Protein Secretases (beta-Secretase)IBA 01/2017
1	nirogacestatIBA 01/2017
1	PTEN Phosphohydrolase (PTEN Phosphatase)IBA 01/2016
1	Tumor Biomarkers (Tumor Markers)IBA 01/2016
1	RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA 01/2016
1	Phenobarbital (Luminal)FDA Link 01/2015
1	Arsenic Trioxide (Trisenox)FDA Link 11/2014
1	Drinking WaterIBA 11/2014
1	ArsenicIBA 11/2014
1	Mechanistic Target of Rapamycin Complex 1IBA 12/2012
1	ADP Ribose Transferases (ADP Ribosyltransferase)IBA 09/2011
1	DNA (Deoxyribonucleic Acid)IBA 09/2011
1	epitumomabIBA 01/2009
1	ImmunosorbentsIBA 09/2006
1	Filgrastim (Neupogen)FDA Link 04/2006
1	Doxorubicin (Adriamycin)FDA LinkGeneric 04/2006
1	Tamoxifen FDA LinkGeneric 04/2006
1	ErbB Receptors (EGF Receptor)IBA 04/2006

Therapy/Procedure

23	Therapeutics 01/2022 - 01/2003
14	Drug Therapy (Chemotherapy) 01/2021 - 05/2004
3	Radiotherapy 01/2015 - 04/2006
3	Aftercare (After-Treatment) 12/2006 - 01/2003
2	Immunotherapy 11/2019 - 01/2010
2	Operative Surgical Procedures 01/2015 - 01/2015
1	Neoadjuvant Therapy 01/2020
1	Prophylactic Mastectomy 01/2015